Publications
The role of receptor subtype diversity in the CNS
Abstract
The molecular characterization of neuroreceptors and voltage-gated ion channels has revealed that receptor subtype heterogeneity is a common feature of chemical and electrical signal reception. The use of distinct genes encoding receptor subtypes is a favoured mechanism for generation of this diversity. We propose that the significance of the multiplicity and diversity of signal reception proteins is to increase the information-handling capacity of neurons. This may contribute to neural plasticity.
| Type | Journal |
|---|---|
| ISBN | 0166-2236 (Print) |
| Authors | Schofield, P. R.;Shivers, B. D.;Seeburg, P. H. : |
| Publisher Name | TRENDS IN NEUROSCIENCES |
| Published Date | 1990-01-01 |
| Published Volume | 13 |
| Published Issue | 1 |
| Published Pages | 8-11 |
| Status | Published in-print |
| URL link to publisher's version | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1688675 |