Publications
Staying alive--naive CD4(+) T cell homeostasis
Abstract
The immune system must maintain a broad repertoire of naive T cells in order to respond to the diverse range of pathogens that it will encounter over the course of a lifetime. Although it is known that contact with IL-7 is crucial for the survival of naive T cells, the precise intracellular signals that mediate its effects remain obscure. An article in this issue of the European Journal of Immunology has found that IL-7 requires the coordinated action of multiple pathways to maintain naive CD4(+) T cells.
| Type | Journal |
|---|---|
| ISBN | 0014-2980 (Print) |
| Authors | Purton, J. F.;Sprent, J.;Surh, C. D. : |
| Publisher Name | EUROPEAN JOURNAL OF IMMUNOLOGY |
| Published Date | 2007-01-01 |
| Published Volume | 37 |
| Published Issue | 9 |
| Published Pages | 2367-9 |
| Status | Published in-print |
| URL link to publisher's version | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17724689 |
| OpenAccess link to author's accepted manuscript version | https://publications.gimr.garvan.org.au/open-access/2269 |