Publications
The TORC that Gets the GC Cycling
Abstract
The signaling pathways regulating positive selection in germinal centers (GCs) are incompletely understood. Ersching et al. (2017) identify a critical but temporal role for the action of the kinase mechanistic target of rapamycin complex (mTORC1), which promotes key changes in GC B cells and thereby facilitates affinity maturation.
| Type | Journal |
|---|---|
| Authors | Deenick, EK.; Tangye, SG. |
| Responsible Garvan Author | Professor Stuart Tangye |
| Publisher Name | IMMUNITY |
| Published Date | 2017-07-20 |
| Published Volume | 46 |
| Published Pages | 974-976 |
| Status | Published in-print |
| DOI | 10.1016/j.immuni.2017.06.003 |
| OpenAccess link to author's accepted manuscript version | https://publications.gimr.garvan.org.au/open-access/14068 |