Publications
SnapShot: insulin/IGF1 signaling
Abstract
The insulin/IGF1signaling pathway (ISP) plays an essential role in long-term health. Some perturbations in this pathway are associated with diseases such as type 2 diabetes; other perturbations extend lifespan in worms, flies, and mice. The ISP regulates many biological processes, including energy storage, apoptosis, transcription, and cellular homeostasis. Such regulation involves precise rewiring of temporal events in protein phosphorylation networks. For an animated version of this Enhanced SnapShot, please visit http://www.cell.com/cell/enhanced/odonoghue.
| Type | Journal |
|---|---|
| ISBN | 1097-4172 (Electronic) 0092-8674 (Linking) |
| Authors | Ma, D. K. ; Stolte, C. ; Krycer, J. R. ; James, D. E. ; O'Donoghue, S. I.; |
| Publisher Name | CELL |
| Published Date | 2015-01-01 |
| Published Volume | 161 |
| Published Issue | 4 |
| Published Pages | 948-948 e1 |
| Status | Published in-print |
| URL link to publisher's version | http://www.ncbi.nlm.nih.gov/pubmed/25957692 |