Publications
Monogenic mutations differentially impact the quantity and quality of T follicular helper cells in human primary immunodeficiencies
Abstract
Background: T follicular helper (Tfh) cells underpin T-cell dependent humoral immunity and the success of most vaccines. Tfh cells also contribute to human immune disorders such as autoimmunity, immunodeficiency and malignancy. Understanding the molecular requirements for the generation and function of Tfh cells will provide strategies for targeting these cells to modulate their behavior in the setting of these immunological abnormalities.
| Type | Journal |
|---|---|
| Authors | Ma, C. S.; Wong, N.; Rao, G.; Avery, D. T.; Torpy, J.; Hambridge, T.; Bustamante, J.; Okada, S.; Stoddard, J. L.; Deenick, E. K.; Pelham, S. J.; Payne, K.; Boisson-Dupuis, S.; Puel, A.; Kobayashi, M.; Arkwright, P. D.; Kilic, S. S.; El Baghdadi, J.; Nonoyama, S.; Minegishi, Y.; Mahdaviani, S. A.; Mansouri, D.; Bousfiha, A.; Blincoe, A. K.; French, M. A.; Hsu, P.; Campbell, D. E.; Stormon, M. O.; Wong, M.; Adelstein, S.; Smart, J. M.; Fulcher, D. A.; Cook, M. C.; Phan, T. G.; Stepensky, P.; Boztug, K.; Kansu, A.; Ikinciogullari, A.; Baumann, U.; Beier, R.; Roscioli, T.; Ziegler, J. B.; Gray, P.; Picard, C.; Grimbacher, B.; Warnatz, K.; Holland, S. M.; Casanova, J. L.; Uzel, G.; Tangye, S. G.; |
| Responsible Garvan Author | Associate Professor Cindy Ma |
| Publisher Name | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY |
| Published Date | 2015-07-08 |
| Published Volume | 136 |
| Published Issue | 4 |
| Published Pages | 993-1006 e1 |
| Status | Published in-print |
| URL link to publisher's version | http://www.ncbi.nlm.nih.gov/pubmed/26162572 |
| OpenAccess link to author's accepted manuscript version | https://publications.gimr.garvan.org.au/open-access/12634 |