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LOX-1 unlocks human plasma cell potential

Abstract

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is best known for promoting atherosclerosis. In this issue of Immunity, Joo et al. (2014) find that dendritic cells triggered through LOX-1 can directly support plasmablast production via the production of the cytokines APRIL and BAFF.

Type Journal
Authors Brink, R.
Responsible Garvan Author Professor Robert Brink
Publisher Name IMMUNITY
Published Date 2014-10-17
Published Volume 41
Published Issue 4
Published Pages 507-8
Status Published in-print
DOI 10.1016/j.immuni.2014.09.019
URL link to publisher's version http://www.ncbi.nlm.nih.gov/pubmed/25367564
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/12326