Publications

Abstract

To evaluate the relationship between waist-to-height ratio (WHtR) and glucose and lipid metabolism in Han adolescents aged 13-15 years. A study was conducted on 1665 Han adolescents aged 13-15 years. Measurements included height, weight, waist circumference, fasting plasma glucose(FPG), triglyceride and high-density lipoprotein cholesterol. The subjects were divided into two groups according to WHtR. Compared with the control group (n=1340,WHtR < 0.46), the abdominal obesity group(n=325,WHtRe""0.46) had significantly higher levels of body mass index (BMI) (26.3 +/- 3.6 vs 18.9 +/- 2.3), WHtR (0.51 +/- 0.04 vs 0.40 +/- 0.03), FPG (4.99 +/- 0.48 vs 4.86 +/- 0.46), and triglyceride (1.21 +/- 0.62 vs 0.87 +/- 0.41), and a lower level of high-density lipoprotein cholesterol (1.26 +/- 0.27 vs 1.46 +/- 0.30) (P < 0.01). Logistic regression analysis showed that after controlling for age, sex and BMI, the elevated FPG and dyslipidemia risk odds ratios of the abdominal obesity group were 1.954 (95% CI:1.250 similar to 3.054) and 2.012 (95% CI:1.204 similar to 3.362) (P < 0.01) respectively. When clustered, the odds ratio of elevated FPG and dyslipidemia was 6.659 (95% CI: 1.337 similar to 33.159) (P < 0.01). The waist-to-height ratio is an appropriate measure to assess dyslipidemic-diabetic adolescents and should be used to guide early intervention with the aim of future prevention of these linked diseases.