Publications
MicroRNAs in common diseases and potential therapeutic applications
Abstract
1. Evidence gathered in the last few years has revealed microRNAs (miRNAs) fine-tune gene expression and play an instrumental role in various cellular processes including cell growth, differentiation, proliferation and apoptosis. 2. This review summarizes current knowledge of miRNA-pathways in the pathogenesis of cancer, cardiac diseases, neurodegenerative diseases, diabetes, autoimmune/inflammatory diseases and infection. 3. There is a great promise to target miRNAs as a novel approach to treat human diseases. 4. MiRNA-based therapies are being examined in both animal model studies and human clinical trials.
| Type | Journal |
|---|---|
| ISBN | 0305-1870 (Linking) |
| Authors | Tsai, L. M.; Yu, D.; |
| Responsible Garvan Author | (missing name) |
| Publisher Name | CLIN EXP PHARMACOL P |
| Published Date | 2010-01-01 |
| Published Volume | 37 |
| Published Issue | 1 |
| Published Pages | 102-107 |
| Status | Published in-print |
| URL link to publisher's version | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19671070 |
| OpenAccess link to author's accepted manuscript version | https://publications.gimr.garvan.org.au/open-access/10573 |