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Glimpsing the real CD4+ T cell response

Abstract

Current views on how CD4+ T cells respond to antigen are based largely on highly artificial systems. A highly sensitive approach that allows normal T cell responses to be followed under physiological conditions overturns some of our existing ideas about CD4+ T cell differentiation.

Type Journal
ISBN 1529-2916 (Electronic) 1529-2908 (Linking)
Authors Surh, C.D.; Sprent, J.:
Publisher Name NATURE IMMUNOLOGY
Published Date 2010-03-01
Published Volume 11
Published Issue 1
Published Pages 47-9
Status Published in-print
DOI ni0110-47 [pii] 10.1038/ni0110-47
URL link to publisher's version http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20016511
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/10497