Publications
The Evidence for Allogeneic Hematopoietic Stem Cell Transplantation for Congenital Neutrophil Disorders: A Comprehensive Review by the Inborn Errors Working Party Group of the EBMT
Abstract
Congenital disorders of the immune system affecting maturation and/or function of phagocytic leucocytes can result in severe infectious and inflammatory complications with high mortality and morbidity. Further complications include progression to MDS/AML in some cases. Allogeneic stem cell transplantation is the only curative treatment for most patients with these diseases. In this review, we provide a detailed update on indications and outcomes of alloHSCT for congenital neutrophil disorders, based on data from the available literature.
Type | Journal |
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ISBN | 2296-2360 (Print) 2296-2360 (Linking) |
Authors | Bakhtiar, S.; Shadur, B.; Stepensky, P. |
Responsible Garvan Author | Dr Bella Shadur |
Publisher Name | Frontiers in Pediatrics |
Published Date | 2019-10-24 |
Published Volume | 7 |
Published Pages | 436 |
Status | Always Electronic |
DOI | 10.3389/fped.2019.00436 |
URL link to publisher's version | https://www.ncbi.nlm.nih.gov/pubmed/31709206 |