Publications
B cell-intrinsic requirement for STK4 in humoral immunity in mice and humans
Abstract
Humoral immune defects are described in 9 patients from 5 families with STK4 deficiency. A mouse model carrying the novel p.Y88del show that these defects are intrinsic to the B cells.
Type | Journal |
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ISBN | 1097-6825 (Electronic) 0091-6749 (Linking) |
Authors | Moran, I.; Avery, D. T.; Payne, K.; Lenthall, H.; Davies, E. G.; Burns, S.; Ip, W.; Oleastro, M. M.; Reisli, I.; Guner, S.; Keles, S.; Notarangelo, L.; Deenick, E. K.; Goodnow, C. C.; Zahra, D.; Brink, R.; Circa; Wong, M.; Tangye, S. G.; Ma, C. S.; Phan, T. G. |
Responsible Garvan Author | Professor Tri Phan |
Publisher Name | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY |
Published Date | 2019-06-01 |
Published Volume | 143 |
Published Issue | 6 |
Published Pages | 2302-2305 |
Status | Published in-print |
DOI | 10.1016/j.jaci.2019.02.010 |
URL link to publisher's version | https://www.ncbi.nlm.nih.gov/pubmed/30796983 |