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Is it dead or alive? TLR8 can tell

Abstract

The sensing of viable pathogens by the receptor TLR8 on human monocytes provides key signals that initiate the differentiation of naive CD4+ T cells into follicular helper T cells. Targeting TLR8 might represent a novel approach for improving immunity following vaccination

Type Journal
ISBN 1529-2916 (Electronic) 1529-2908 (Linking)
Authors Tangye, S. G.
Responsible Garvan Author Professor Stuart Tangye
Publisher Name NATURE IMMUNOLOGY
Published Date 2018-03-27
Published Volume 19
Published Issue 4
Published Pages 324-326
Status Published in-print
DOI 10.1038/s41590-018-0070-x
URL link to publisher's version https://www.ncbi.nlm.nih.gov/pubmed/29556003