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TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma
Lundy, J.; Gearing, L. J.; Gao, H.; West, A. C.; McLeod, L.; Deswaerte, V.; Yu, L.; Porazinski, S.; Pajic, M.; Hertzog, P. J.; Croagh, D.; Jenkins, B. J.
ONCOGENE 2021 10.1038/s41388-021-01992-2
Development and validation of the risk engine for an Australian Health Economics Model of Osteoporosis
Si, L.; Eisman, J. A.; Winzenberg, T.; Sanders, K. M.; Center, J. R.; Nguyen, T. V.; Tran, T.; Palmer, A. J.
OSTEOPOROSIS INTERNATIONAL 2021 10.1007/s00198-021-05955-x
Role of Pancreatic Stellate Cell-Derived Exosomes in Pancreatic Cancer-Related Diabetes: A Novel Hypothesis
Perera, C. J.; Falasca, M.; Chari, S. T.; Greenfield, J. R.; Xu, Z.; Pirola, R. C.; Wilson, J. S.; Apte, M. V.
Cancers 13 (20) :5224, 2021 10.3390/cancers13205224
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status
Murphy, K. J.; Reed, D. A.; Vennin, C.; Conway, J. R. W.; Nobis, M.; Yin, J. X.; Chambers, C. R.; Pereira, B. A.; Lee, V.; Filipe, E. C.; Trpceski, M.; Ritchie, S.; Lucas, M. C.; Warren, S. C.; Skhinas, J. N.; Magenau, A.; Metcalf, X. L.; Stoehr, J.; Major, G.; Parkin, A.; Bidanel, R.; Lyons, R. J.; Zaratzian, A.; Tayao, M.; Da Silva, A.; Abdulkhalek, L.; Australian Pancreatic Genome, Initiative; Australian Pancreatic Cancer Matrix, Atlas; Gill, A. J.; Johns, A. L.; Biankin, A. V.; Samra, J.; Grimmond, S. M.; Chou, A.; Goetz, J. G.; Samuel, M. S.; Lyons, J. G.; Burgess, A.; Caldon, C. E.; Horvath, L. G.; Daly, R. J.; Gadegaard, N.; Wang, Y.; Sansom, O. J.; Morton, J. P.; Cox, T. R.; Pajic, M.; Herrmann, D.; Timpson, P.
Science Advances 7 (40) :eabh0363, 2021 10.1126/sciadv.abh0363
Supporting teachers to use genomics as a context in the classroom: an evaluation of learning resources for high school biology
McKnight, L.; Pearce, A.; Willis, A.; Young, M. A.; Terrill, B.
Journal of Community Genetics 12 (4) :653-662, 2021 10.1007/s12687-021-00550-3
A single-cell tumor immune atlas for precision oncology
Nieto, P.; Elosua-Bayes, M.; Trincado, J. L.; Marchese, D.; Massoni-Badosa, R.; Salvany, M.; Henriques, A.; Nieto, J.; Aguilar-Fernandez, S.; Mereu, E.; Moutinho, C.; Ruiz, S.; Lorden, P.; Chin, V. T.; Kaczorowski, D.; Chan, C. L.; Gallagher, R.; Chou, A.; Planas-Rigol, E.; Rubio-Perez, C.; Gut, I.; Piulats, J. M.; Seoane, J.; Powell, J. E.; Batlle, E.; Heyn, H.
GENOME RESEARCH 31 (10) :1913-1926, 2021 10.1101/gr.273300.120
The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey
Thavaneswaran, S.; Ballinger, M.; Butow, P.; Meiser, B.; Goldstein, D.; Lin, F.; Napier, C.; Thomas, D.; Best, M.
Oncotarget 12 (21) :2169-2176, 2021 10.18632/oncotarget.28076
A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia
Tuong, Z. K.; Lukowski, S. W.; Nguyen, Q. H.; Chandra, J.; Zhou, C.; Gillinder, K.; Bashaw, A. A.; Ferdinand, J. R.; Stewart, B. J.; Teoh, S. M.; Hanson, S. J.; Devitt, K.; Clatworthy, M. R.; Powell, J. E.; Frazer, I. H.
iScience 24 (11) :103326, 2021 10.1016/j.isci.2021.103326
Network-based transcriptomic analysis identifies the genetic effect of COVID-19 to chronic kidney disease patients: A bioinformatics approach
Auwul, M. R.; Zhang, C.; Rahman, M. R.; Shahjaman, M.; Alyami, S. A.; Moni, M. A.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES 28 (10) :5647-5656, 2021 10.1016/j.sjbs.2021.06.015
Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions
Andersson, A.; Larsson, L.; Stenbeck, L.; Salmen, F.; Ehinger, A.; Wu, S. Z.; Al-Eryani, G.; Roden, D.; Swarbrick, A.; Borg, A.; Frisen, J.; Engblom, C.; Lundeberg, J.
Nature Communications 12 (1) :6012, 2021 10.1038/s41467-021-26271-2
GSK-3beta regulates the synaptic expression of NMDA receptors via phosphorylation of phosphatidylinositol 4 kinase type IIalpha
Amici, M.; Lee, Y.; Pope, R. J. P.; Bradley, C. A.; Cole, A.; Collingridge, G. L.
EUROPEAN JOURNAL OF NEUROSCIENCE 54 (8) :6815-6825, 2021 10.1111/ejn.14841
General practitioners' views on genomics, practice and education: A qualitative interview study
Cusack, M. B.; Hickerton, C.; Nisselle, A.; McClaren, B.; Terrill, B.; Gaff, C.; Dunlop, K.; Metcalfe, S.
Australian Journal of General Practice 50 (10) :747-752, 2021 10.31128/AJGP-05-20-5448
Colorimetric histology using plasmonically active microscope slides
Balaur, E.; S, O' Toole; Spurling, A. J.; Mann, G. B.; Yeo, B.; Harvey, K.; Sadatnajafi, C.; Hanssen, E.; Orian, J.; Nugent, K. A.; Parker, B. S.; Abbey, B.
NATURE 598 (7879) :65-71, 2021 10.1038/s41586-021-03835-2
Pirfenidone Reduces Epithelial-Mesenchymal Transition and Spheroid Formation in Breast Carcinoma through Targeting Cancer-Associated Fibroblasts (CAFs)
Es, H. A.; Cox, T. R.; Sarafraz-Yazdi, E.; Thiery, J. P.; Warkiani, M. E.
Cancers (Basel) 13 (20) :5118, 2021 10.3390/cancers13205118
Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase
Lin, H. M.; Mak, B.; Yeung, N.; Huynh, K.; Meikle, T. G.; Mellett, N. A.; Kwan, E. M.; Fettke, H.; Tran, B.; Davis, I. D.; Mahon, K. L.; Zhang, A.; Stockler, M. R.; Briscoe, K.; Marx, G.; Crumbaker, M.; Stricker, P. D.; Du, P.; Yu, J.; Jia, S.; Scheinberg, T.; Fitzpatrick, M.; Bonnitcha, P.; Sullivan, D. R.; Joshua, A. M.; Azad, A. A.; Butler, L. M.; Meikle, P. J.; Horvath, L. G.
EBioMedicine 72 :103625, 2021 10.1016/j.ebiom.2021.103625
The expansion of human T-bet(high)CD21(low) B cells is T cell dependent
Keller, B.; Strohmeier, V.; Harder, I.; Unger, S.; Payne, K. J.; Andrieux, G.; Boerries, M.; Felixberger, P. T.; Landry, J. J. M.; Nieters, A.; Rensing-Ehl, A.; Salzer, U.; Frede, N.; Usadel, S.; Elling, R.; Speckmann, C.; Hainmann, I.; Ralph, E.; Gilmour, K.; Wentink, M. W. J.; van der Burg, M.; Kuehn, H. S.; Rosenzweig, S. D.; Kolsch, U.; von Bernuth, H.; Kaiser-Labusch, P.; Gothe, F.; Hambleton, S.; Vlagea, A. D.; Garcia Garcia, A.; Alsina, L.; Markelj, G.; Avcin, T.; Vasconcelos, J.; Guedes, M.; Ding, J. Y.; Ku, C. L.; Shadur, B.; Avery, D. T.; Venhoff, N.; Thiel, J.; Becker, H.; Erazo-Borras, L.; Trujillo-Vargas, C. M.; Franco, J. L.; Fieschi, C.; Okada, S.; Gray, P. E.; Uzel, G.; Casanova, J. L.; Fliegauf, M.; Grimbacher, B.; Eibel, H.; Ehl, S.; Voll, R. E.; Rizzi, M.; Stepensky, P.; Benes, V.; Ma, C. S.; Bossen, C.; Tangye, S. G.; Warnatz, K.
Science Immunology 6 (64) :eabh0891, 2021 10.1126/sciimmunol.abh0891