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Oral Squamous Cell Carcinoma in Young Patients Show Higher Rates of EGFR Amplification: Implications for Novel Personalized Therapy
Satgunaseelan, L.; Porazinski, S.; Strbenac, D.; Istadi, A.; Willet, C.; Chew, T.; Sadsad, R.; Palme, C. E.; Lee, J. H.; Boyer, M.; Yang, J. Y. H.; Clark, J. R.; Pajic, M.; Gupta, R.
Frontiers in Oncology 11 :750852, 2021 10.3389/fonc.2021.750852
Cognitive decline is associated with an accelerated rate of bone loss and increased fracture risk in women: a prospective study from the Canadian Multicentre Osteoporosis Study
Bliuc, D.; Tran, T.; Adachi, J. D.; Atkins, G. J.; Berger, C.; van den Bergh, J.; Cappai, R.; Eisman, J. A.; van Geel, T.; Geusens, P.; Goltzman, D.; Hanley, D. A.; Josse, R.; Kaiser, S.; Kovacs, C. S.; Langsetmo, L.; Prior, J. C.; Nguyen, T. V.; Solomon, L. B.; Stapledon, C.; Center, J. R.; Canadian Multicentre Osteoporosis Study Research, Group
JOURNAL OF BONE AND MINERAL RESEARCH 2021 10.1002/jbmr.4402
Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer
Singhal, D.; Hahn, C. N.; Feurstein, S.; Wee, L. Y. A.; Moma, L.; Kutyna, M. M.; Chhetri, R.; Eshraghi, L.; Schreiber, A. W.; Feng, J.; Wang, P. P.; Babic, M.; Parker, W. T.; Gao, S.; Moore, S.; Das, S.; Thomas, D.; Pattnaik, S.; Brown, A. L.; D'Andrea, R. J.; Poplawski, N. K.; Thomas, D.; Scott, H. S.; Godley, L. A.; Hiwase, D. K.
LEUKEMIA 2021 10.1038/s41375-021-01246-w
Bioinformatics and system biology approaches to identify the diseasome and comorbidities complexities of SARS-CoV-2 infection with the digestive tract disorders
Nashiry, M. A.; Sumi, S. S.; Sharif Shohan, M. U.; Alyami, S. A.; Azad, A. K. M.; Moni, M. A.
BRIEFINGS IN BIOINFORMATICS 2021 10.1093/bib/bbab126
Anti-Ro60 and anti-Ro52/TRIM21: Two distinct autoantibodies in systemic autoimmune diseases
Lee, A. Y. S.; Reed, J. H.; Gordon, T. P.
JOURNAL OF AUTOIMMUNITY 124 :102724, 2021 10.1016/j.jaut.2021.102724
A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia
Mohamed, S. M. A.; Wohlmann, A.; Schofield, P.; Sia, K. C. S.; McCalmont, H.; Savvides, S. N.; Verstraete, K.; Kavallaris, M.; Christ, D.; Friedrich, K. H.; Bayat, N.; Lock, R. B.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 190 :214-223, 2021 10.1016/j.ijbiomac.2021.08.194
Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation
Jonkhout, N.; Cruciani, S.; Santos Vieira, H. G.; Tran, J.; Liu, H.; Liu, G.; Pickford, R.; Kaczorowski, D.; Franco, G. R.; Vauti, F.; Camacho, N.; Abedini, S. S.; Najmabadi, H.; Ribas de Pouplana, L.; Christ, D.; Schonrock, N.; Mattick, J. S.; Novoa, E. M.
RNA Biology :1-15, 2021 10.1080/15476286.2021.1881291
Multimodality Treatment Improves Locoregional Control, Progression-Free and Overall Survival in Patients with Anaplastic Thyroid Cancer: A Retrospective Cohort Study Comparing Oncological Outcomes and Morbidity between Multimodality Treatment and Limited Treatment
Jonker, P. K. C.; Turchini, J.; Kruijff, S.; Lin, J. F.; Gill, A. J.; Eade, T.; Aniss, A.; Clifton-Bligh, R.; Learoyd, D.; Robinson, B.; Tsang, V.; Glover, A.; Sidhu, S.; Sywak, M.
ANNALS OF SURGICAL ONCOLOGY 2021 10.1245/s10434-021-10146-3
ENZA-p trial protocol: a randomized phase II trial using prostate-specific membrane antigen as a therapeutic target and prognostic indicator in men with metastatic castration-resistant prostate cancer treated with enzalutamide (ANZUP 1901)
Emmett, L.; Subramaniam, S.; Joshua, A. M.; Crumbaker, M.; Martin, A.; Zhang, A. Y.; Rana, N.; Langford, A.; Mitchell, J.; Yip, S.; Francis, R.; Hofman, M. S.; Sandhu, S.; Azad, A.; Gedye, C.; McJannett, M.; Stockler, M. R.; Davis, I. D.; Australian, New Zealand Urogenital Prostate Cancer Trials Group the Enza-p investigators
BJU International 2021 10.1111/bju.15491
Longitudinal patterns in fear of cancer progression in patients with rare, advanced cancers undergoing comprehensive tumour genomic profiling
Butow, P.; Muller, F.; Napier, C. E.; Bartley, N.; Ballinger, M. L.; Biesecker, B.; Juraskova, I.; Meiser, B.; Schlub, T. E.; Thomas, D. M.; Goldstein, D.; Best, M. C.; Members of the PiGeOn, Project
PSYCHO-ONCOLOGY 2021 10.1002/pon.5764
Mammary Tumor Organoid Culture in Non-Adhesive Alginate for Luminal Mechanics and High-Throughput Drug Screening
Fang, G.; Lu, H.; Rodriguez de la Fuente, L.; Law, A. M. K.; Lin, G.; Jin, D.; Gallego-Ortega, D.
Advanced Science :e2102418, 2021 10.1002/advs.202102418
The Sequencing Quality Control 2 study: establishing community standards for sequencing in precision medicine
Mercer, T. R.; Xu, J.; Mason, C. E.; Tong, W.; Consortium, Maqc Seqc
GENOME BIOLOGY 22 (1) :306, 2021 10.1186/s13059-021-02528-3
MDM2 as a Rational Target for Intervention in CDK4/6 Inhibitor Resistant, Hormone Receptor Positive Breast Cancer
Portman, N.; Chen, J.; Lim, E.
Frontiers in Oncology 11 :777867, 2021 10.3389/fonc.2021.777867
Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency
Yap, J. Y.; Moens, L.; Lin, M. W.; Kane, A.; Kelleher, A.; Toong, C.; Wu, K. H. C.; Sewell, W. A.; Phan, T. G.; Hollway, G. E.; Enthoven, K.; Gray, P. E.; Casas-Martin, J.; Wouters, C.; De Somer, L.; Hershfield, M.; Bucciol, G.; Delafontaine, S.; Ma, C. S.; Tangye, S. G.; Meyts, I.
JOURNAL OF CLINICAL IMMUNOLOGY 41 (8) :1915-1935, 2021 10.1007/s10875-021-01141-0
Return of individual research results from genomic research: A systematic review of stakeholder perspectives
Vears, D. F.; Minion, J. T.; Roberts, S. J.; Cummings, J.; Machirori, M.; Blell, M.; Budin-Ljosne, I.; Cowley, L.; Dyke, S. O. M.; Gaff, C.; Green, R.; Hall, A.; Johns, A. L.; Knoppers, B. M.; Mulrine, S.; Patch, C.; Winkler, E.; Murtagh, M. J.
PLoS One 16 (11) :e0258646, 2021 10.1371/journal.pone.0258646
Lack of neuropeptide FF signalling in mice leads to reduced repetitive behavior, altered drinking behavior, and fuel type selection
Zhang, L.; Koller, J.; Ip, C. K.; Gopalasingam, G.; Bajaj, N.; Lee, N. J.; Enriquez, R. F.; Herzog, H.
FASEB JOURNAL 35 (11) :e21980, 2021 10.1096/fj.202100703R