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Cost-effectiveness of population-based BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2 mutation testing in unselected general population women
Manchanda, R.; Patel, S.; Gordeev, V. S.; Antoniou, A. C.; Smith, S.; Lee, A.; Hopper, J. L.; MacInnis, R. J.; Turnbull, C.; Ramus, S. J.; Gayther, S. A.; Pharoah, P. D. P.; Menon, U.; Jacobs, I.; Legood, R.
JNCI-Journal of the National Cancer Institute 110 (7) :714-725, 2018 10.1093/jnci/djx265
OpenAccess publication Female sex hormones are necessary for the metabolic effects mediated by loss of Interleukin 18 signaling
Lindegaard, B.; Abildgaard, J.; Heywood, S. E.; Pedersen, B. K.; Febbraio, M. A.
Molecular Metabolism 12 :89-97, 2018 10.1016/j.molmet.2018.04.005
OpenAccess publication APP deficiency results in resistance to obesity but impairs glucose tolerance upon high fat feeding
Czeczor, J. K.; Genders, A. J.; Aston-Mourney, K.; Connor, T.; Hall, L. G.; Hasebe, K.; Ellis, M.; De Jong, K. A.; Henstridge, D. C.; Meikle, P. J.; Febbraio, M. A.; Walder, K.; McGee, S. L.
JOURNAL OF ENDOCRINOLOGY 237 (3) :311-322, 2018 10.1530/JOE-18-0051
The Emperor's New Clothes: What Randomized Controlled Trials Don't Cover
Eisman, J. A.; Geusens, P.; van den Bergh, J.
JOURNAL OF BONE AND MINERAL RESEARCH 33 (8) :1394-1396, 2018 10.1002/jbmr.3539
From vesicle to cytosol
Rogers, M. J.; Munoz, M. A.
eLife 7 :e38847, 2018 10.7554/eLife.38847
CogStack - experiences of deploying integrated information retrieval and extraction services in a large National Health Service Foundation Trust hospital
Jackson, R.; Kartoglu, I.; Stringer, C.; Gorrell, G.; Roberts, A.; Song, X.; Wu, H.; Agrawal, A.; Lui, K.; Groza, T.; Lewsley, D.; Northwood, D.; Folarin, A.; Stewart, R.; Dobson, R.
BMC Medical Informatics and Decision Making 18 (1) :47, 2018 10.1186/s12911-018-0623-9
OpenAccess publication Interrogation of a longitudinal, national pharmacy claims dataset to explore factors that predict the need for add-on therapy in older and socioeconomically disadvantaged Australians with type 2 diabetes mellitus patients (T2DM)
Kumar, S. S.; McManus, H.; Radovich, T.; Greenfield, J. R.; Viardot, A.; Williams, K. M.; Cronin, P.; Day, R. O.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 2018 10.1007/s00228-018-2506-5
Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors
Hoque, M.; Abbassi, R. H.; Froio, D.; Man, J.; Johns, T. G.; Stringer, B. W.; Day, B. W.; Pajic, M.; Kassiou, M.; Munoz, L.
PHARMACOLOGICAL RESEARCH 134 :166-178, 2018 10.1016/j.phrs.2018.06.023
Prediction of changes in bone mineral density in the elderly: contribution of "osteogenomic profile"
Ho-Le, T. P.; Pham, H. M.; Center, J. R.; Eisman, J. A.; Nguyen, H. T.; Nguyen, T. V.
Archives of Osteoporosis 13 (1) :68, 2018 10.1007/s11657-018-0480-2
Sex hormone-binding globulin is a biomarker associated with nonvertebral fracture in men on dialysis therapy
Aleksova, J.; Wong, P.; McLachlan, R.; Choy, K. W.; Ebeling, P. R.; Milat, F.; Elder, G. J.
KIDNEY INTERNATIONAL 94 (2) :372-380, 2018 10.1016/j.kint.2018.02.021
OpenAccess publication Dissecting multi-protein signaling complexes by Bimolecular Complementation Affinity Purification (BiCAP)
Hastings, J. F.; Han, J. Z. R.; Shearer, R. F.; Kennedy, S. P.; Iconomou, M.; Saunders, D. N.; Croucher, D. R.
Jove-Journal of Visualized Experiments (136) :e57109, 2018 10.3791/57109
Immunotherapy in Non-Small Cell Lung Cancer: Shifting Prognostic Paradigms
Barnet, M. B.; Cooper, W. A.; Boyer, M. J.; Kao, S.
Journal of Clinical Medicine 7 (6) :E151, 2018 10.3390/jcm7060151
Rho kinase inhibition blocks pancreatic ductal adenocarinoma invasion and tumor growth
Rath, N.; Munro, J.; Cutiongco, M. F.; Jagiello, A.; Gadegaard, N.; McGarry, L.; Unbekandt, M.; Michalopoulou, E.; Kamphorst, J. J.; Sumpton, D.; Mackay, G.; Vennin, C.; Pajic, M.; Timpson, P.; Olson, M. F.
CLINICAL CANCER RESEARCH 78 (12) :3321-3336, 2018 10.1158/0008-5472.Can-17-1339
OpenAccess publication Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis
Dragoljevic, D.; Kraakman, M. J.; Nagareddy, P. R.; Ngo, D.; Shihata, W.; Kammoun, H. L.; Whillas, A.; Lee, M. K. S.; Al-Sharea, A.; Pernes, G.; Flynn, M. C.; Lancaster, G. I.; Febbraio, M. A.; Chin-Dusting, J.; Hanaoka, B. Y.; Wicks, I. P.; Murphy, A. J.
EUROPEAN HEART JOURNAL 39 (23) :2158-2167, 2018 10.1093/eurheartj/ehy119
OpenAccess publication A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
Papachristou, E. K.; Kishore, K.; Holding, A. N.; Harvey, K.; Roumeliotis, T. I.; Chilamakuri, C. S. R.; Omarjee, S.; Chia, K. M.; Swarbrick, A.; Lim, E.; Markowetz, F.; Eldridge, M.; Siersbaek, R.; D'Santos, C. S.; Carroll, J. S.
Nature Communications 9 (1) :2311, 2018 10.1038/s41467-018-04619-5
OpenAccess publication Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer
Conway, J. R. W.; Warren, S. C.; Herrmann, D.; Murphy, K. J.; Cazet, A. S.; Vennin, C.; Shearer, R. F.; Killen, M. J.; Magenau, A.; Melenec, P.; Pinese, M.; Nobis, M.; Zaratzian, A.; Boulghourjian, A.; Da Silva, A. M.; Del Monte-Nieto, G.; Adam, A. S. A.; Harvey, R. P.; Haigh, J. J.; Wang, Y.; Croucher, D. R.; Sansom, O. J.; Pajic, M.; Caldon, C. E.; Morton, J. P.; Timpson, P.
Cell Reports 23 (11) :3312-3326, 2018 10.1016/j.celrep.2018.05.038