Publications

6444 items matching your search terms.

Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants

Nguyen, E. V.; Centenera, M. M.; Moldovan, M.; Das, R.; Irani, S.; Vincent, A. D.; Chan, H.; Horvath, L. G.; Lynn, D. J.; Daly, R. J.; Butler, L. M.

MOLECULAR & CELLULAR PROTEOMICS 17 (8) :1470-1486, 2018 10.1074/mcp.RA118.000633

A randomised, open-label, parallel group phase 2 study of antisense oligonucleotide therapy in acromegaly

Trainer, P. J.; Newell-Price, J. D. C.; Ayuk, J.; Aylwin, S. J. B.; Rees, A.; Drake, W.; Chanson, P.; Brue, T.; Webb, S. M.; Fajardo, C.; Aller, J.; McCormack, A. I.; Torpy, D. J.; Tachas, G.; Atley, L.; Ryder, D.; Bidlingmaier, M.

EUROPEAN JOURNAL OF ENDOCRINOLOGY 179 (2) :97-108, 2018 10.1530/eje-18-0138

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation

Ikonomopoulou, M. P.; Fernandez-Rojo, M. A.; Pineda, S. S.; Cabezas-Sainz, P.; Winnen, B.; Morales, R. A. V.; Brust, A.; Sanchez, L.; Alewood, P. F.; Ramm, G. A.; Miles, J. J.; King, G. F.

Scientific Reports 8 (1) :11519, 2018 10.1038/s41598-018-29826-4

Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake

Small, L.; Brandon, A. E.; Quek, L. E.; Krycer, J. R.; James, D. E.; Turner, N.; Cooney, G. J.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 315 (2) :E258-E266, 2018 10.1152/ajpendo.00386.2017

Understanding Immune Tolerance of Cancer: Re-Purposing Insights from Fetal Allografts and Microbes

Barnet, M. B.; Blinman, P.; Cooper, W.; Boyer, M. J.; Kao, S.; Goodnow, C. C.

BIOESSAYS 40 (8) :e1800050, 2018 10.1002/bies.201800050

Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study

Yang, X.; Leslie, G.; Gentry-Maharaj, A.; Ryan, A.; Intermaggio, M.; Lee, A.; Kalsi, J. K.; Tyrer, J.; Gaba, F.; Manchanda, R.; Pharoah, P. D. P.; Gayther, S. A.; Ramus, S. J.; Jacobs, I.; Menon, U.; Antoniou, A. C.

JOURNAL OF MEDICAL GENETICS 55 (8) :546-554, 2018 10.1136/jmedgenet-2018-105313

MASTL overexpression promotes chromosome instability and metastasis in breast cancer

Rogers, S.; McCloy, R. A.; Parker, B. L.; Gallego-Ortega, D.; Law, A. M. K.; Chin, V. T.; Conway, J. R. W.; Fey, D.; Millar, E. K. A.; O'Toole, S.; Deng, N.; Swarbrick, A.; Chastain, P. D.; Cesare, A. J.; Timpson, P.; Caldon, C. E.; Croucher, D. R.; James, D. E.; Watkins, D. N.; Burgess, A.

ONCOGENE 37 (33) :4518-4533, 2018 10.1038/s41388-018-0295-z

Identification of novel response and predictive biomarkers to Hsp90 inhibitors through mass spectrometry-based proteomic profiling of patient-derived prostate tumor explants

Nguyen, E. V.; Centenera, M. M.; Moldovan, M.; Das, R.; Irani, S.; Vincent, A. D.; Chan, H.; Horvath, L. G.; Lynn, D. J.; Daly, R. J.; Butler, L. M.

MOLECULAR & CELLULAR PROTEOMICS 17 (8) :1470-1486, 2018 10.1074/mcp.RA118.000633

Hidden hearing loss and endbulbs of Held: Evidence for central pathology before detection of ABR threshold increases

Muniak, M. A.; Ayeni, F. E.; Ryugo, D. K.

HEARING RESEARCH 364 (July 18) :104-117, 2018 10.1016/j.heares.2018.03.021

Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations

Nguyen, Q. H.; Lukowski, S. W.; Chiu, H. S.; Senabouth, A.; Bruxner, T. J. C.; Christ, A. N.; Palpant, N. J.; Powell, J. E.

GENOME RESEARCH 28 (7) :1053-1066, 2018 10.1101/gr.223925.117

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

Li, J.; Choi, P. S.; Chaffer, C. L.; Labella, K.; Hwang, J. H.; Giacomelli, A. O.; Kim, J. W.; Ilic, N.; Doench, J. G.; Ly, S. H.; Dai, C.; Hagel, K.; Hong, A. L.; Gjoerup, O.; Goel, S.; Ge, J. Y.; Root, D. E.; Zhao, J. J.; Brooks, A. N.; Weinberg, R. A.; Hahn, W. C.

eLife 7 :e37184, 2018 10.7554/eLife.37184

Recovering gene interactions from single-sell data using data diffusion

van Dijk, D.; Sharma, R.; Nainys, J.; Yim, K.; Kathail, P.; Carr, A. J.; Burdziak, C.; Moon, K. R.; Chaffer, C. L.; Pattabiraman, D.; Bierie, B.; Mazutis, L.; Wolf, G.; Krishnaswamy, S.; Pe'er, D.

CELL 174 (3) :716-729, 2018 10.1016/j.cell.2018.05.061

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

Ramnath, D.; Irvine, K. M.; Lukowski, S. W.; Horsfall, L. U.; Loh, Z.; Clouston, A. D.; Patel, P. J.; Fagan, K. J.; Iyer, A.; Lampe, G.; Stow, J. L.; Schroder, K.; Fairlie, D. P.; Powell, J. E.; Powell, E. E.; Sweet, M. J.

Journal of Clinical Investigation Insight 3 (14) :e120274, 2018 10.1172/jci.insight.120274

Discriminating the earliest stages of mammary carcinoma using myoepithelial and proliferative markers

Duivenvoorden, H. M.; Spurling, A.; O'Toole, S. A.; Parker, B. S.

PLoS One 13 (7) :e0201370, 2018 10.1371/journal.pone.0201370

Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

Marini, K. D.; Croucher, D. R.; McCloy, R. A.; Vaghjiani, V.; Gonzalez-Rajal, A.; Hastings, J. F.; Chin, V.; Szczepny, A.; Kostyrko, K.; Marquez, C.; Jayasekara, W. S. N.; Alamgeer, M.; Boolell, V.; Han, J. Z. R.; Waugh, T.; Lee, H. C.; Oakes, S. R.; Kumar, B.; Harrison, C. A.; Hedger, M. P.; Lorensuhewa, N.; Kita, B.; Barrow, R.; Robinson, B. W.; de Kretser, D. M.; Wu, J.; Ganju, V.; Sweet-Cordero, E. A.; Burgess, A.; Martelotto, L. G.; Rossello, F. J.; Cain, J. E.; Watkins, D. N.

Science Translational Medicine 10 (451) :eaat3504, 2018 10.1126/scitranslmed.aat3504

Whole Genome Sequencing Improves Outcomes of Genetic Testing in Patients With Hypertrophic Cardiomyopathy

Bagnall, R. D.; Ingles, J.; Dinger, M. E.; Cowley, M. J.; Ross, S. B.; Minoche, A. E.; Lal, S.; Turner, C.; Colley, A.; Rajagopalan, S.; Berman, Y.; Ronan, A.; Fatkin, D.; Semsarian, C.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 72 (4) :419-429, 2018 10.1016/j.jacc.2018.04.078